By Stephen D. Wiviott
* attracts from services of leaders in antiplatelet remedy* Easy-to-use structure permits quick looking* Edited by means of a member of the celebrated TIMI examine crew with long-standing event within the box
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Additional info for Antiplatelet Therapy In Ischemic Heart Disease (American Heart Association Clinical Series)
4 The Impact® cone and plate(let) analyzer. Chapter 2 Assessment of platelet function 23 cone in a standardized cup . After automated staining, platelet adhesion to the cup is evaluated by image analysis software. Advantages of the Impact® include: point-of-care (although, unlike the VerifyNow® device, pipetting of the blood sample is required), simplicity, rapidity, low sample volume, physiologically relevant high shear, and a whole blood system. The assay has been used to monitor GP IIb/IIIa antagonist therapy.
Turbidometric platelet aggregation has been the platelet function test most often used in clinical trials. Several studies have reported that platelet aggregometry can predict major adverse cardiac events (MACE), although the number of MACE in all these studies was low [10–12]. There are major disadvantages to platelet aggregometry as a clinical test of platelet function, including high sample volume, requirement for sample preparation, length of assay time, requirement of a skilled technician and expense .
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Antiplatelet Therapy In Ischemic Heart Disease (American Heart Association Clinical Series) by Stephen D. Wiviott